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Low-dose ozone as an adjunctive approach to recovery from ischaemia–reperfusion injury

Low-dose intravenous ozone therapy

In practice, we see that low-dose intravenous ozone therapy can make a possible supportive contribution to the recovery process. It is regularly observed that patients who use ozone therapy after a heart attack or stroke experience improvements in stamina, mental clarity and stimulus processing. In addition, they often report less rapid fatigue and better resilience in their daily functioning.

The article by Viebahn-Haensler and León Fernández describes the underlying mechanisms of ischaemia–reperfusion injury (I/R injury) and discusses how low doses of medical ozone may have a protective effect in this regard. I/R damage occurs when the blood supply to an organ is temporarily interrupted and then restored, as in the case of a heart attack, stroke or organ transplant. During the reperfusion phase in particular, a sudden increase in reactive oxygen species causes severe oxidative stress. These free radicals damage the mitochondria, leading to disruption of energy metabolism, activation of inflammatory processes and ultimately cell death.

The full article can be found at: Viebahn-Haensler R, León Fernández OS. Protection of Mitochondria, Cells and Organs from Ischemia-Reperfusion Damage Through Preventive Redox Bioregulation by Ozone. Int J Mol Sci. 10 June 2025;26(12):5557. doi: 10.3390/ijms26125557. PMID: 40565022; PMCID: PMC12193139.

 

Disclaimer: Results may vary from person to person and depend on personal circumstances and factors. The examples shown do not guarantee the outcome of your own treatment.

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